10 Best-Selling Infectious Diseases Books Millions Love

Trusted picks by Bill Gates, Jon Najarian, and Pierre Haski highlight these best-selling Infectious Diseases books.

Bill Gates
Jon Najarian
Pierre Haski
Jeff Dean (@)
Indra Nooyi
Vali Nasr
Kyle Bass
Updated on June 28, 2025
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There's something special about books that both critics and crowds love, especially in the urgent field of infectious diseases. The global impact of pandemics and outbreaks has sparked widespread interest in understanding these threats, making infectious diseases books a vital resource. These titles have earned their place among readers because they offer proven value, combining gripping narratives with scientific insight, helping you grasp the complexities of viral and bacterial threats.

Among the experts championing these books, Bill Gates stands out with his extensive work funding global health initiatives, emphasizing the importance of malaria research in The Fever. Meanwhile, Jon Najarian, a seasoned CNBC anchor, points to The Hot Zone for its vivid portrayal of Ebola’s dangers. Pierre Haski, a geopolitical commentator, found The Hot Zone invaluable during viral crises like SARS, showing how these books resonate with professionals facing real-world infectious threats.

While these popular books provide proven frameworks and stories, readers seeking content tailored to their unique Infectious Diseases interests might consider creating a personalized Infectious Diseases book that blends these validated approaches with your specific background and goals. This approach ensures you get targeted, relevant insights without wading through unrelated material.

Best for understanding viral outbreaks
Jon Najarian, co-founder of Investitute and CNBC anchor, highlights a compelling connection between bats and viruses like Ebola and coronavirus, underscoring why he recommends The Hot Zone. He calls it a "scary, but great book on ebola," reflecting how its detailed account deepened his understanding of viral outbreaks and their origins. This insight aligns with the book's popularity among those intrigued by infectious diseases and epidemic threats. Following Najarian, Pierre Haski, a geopolitical commentator and president of Reporters Without Borders, recalls how the book provided valuable perspective during the SARS crisis in Beijing, reinforcing its relevance in times of viral uncertainty.
JN

Recommended by Jon Najarian

Co-Founder @Investitute & CNBC Anchor

I believe both the corona virus and ebola have a bat connection. Scary, but great book on ebola: Hot Zone by Richard Preston (from X)

What started as a gripping investigation into a deadly outbreak, Richard Preston's The Hot Zone plunges you into the terrifying emergence of the Ebola virus. Drawing on his extensive experience as a New Yorker writer and his unique access to scientific and military sources, Preston details the virus's journey from the African rainforest to the suburbs of Washington, D.C. You gain a vivid understanding of virology, epidemic response, and the chilling speed at which such pathogens can spread. The book benefits anyone curious about infectious diseases, whether you're a medical professional, public health official, or simply fascinated by the dynamics of viral outbreaks.

New York Times Bestseller
Adapted into National Geographic Mini-Series
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Best for pandemic history enthusiasts
Jeff Dean, Senior Fellow and SVP at Google AI Research and Health, highlights this book while reflecting on social distancing times, saying, "Thanks for the pointer, @joetimmons79! Also, looks like John Barry, the speaker in the video, is an author, & has an interesting looking book about the 1918 flu (if flu pandemic books while social distancing is your cup of tea: I've added to my queue):" His recommendation aligns with widespread admiration from other experts like Indra Nooyi, former PepsiCo CEO, who found it a compelling historical lens for understanding COVID-19. Their insights suggest this book offers more than history—it provides a framework for grasping the complex interplay of science, politics, and public trust during pandemics, valuable for anyone looking to deepen their understanding of infectious diseases.
JD

Recommended by Jeff Dean

Senior Fellow & SVP, Google AI Research and Health

Thanks for the pointer, @joetimmons79! Also, looks like John Barry, the speaker in the video, is an author, & has an interesting looking book about the 1918 flu (if flu pandemic books while social distancing is your cup of tea: I've added to my queue): (from X)

When John M. Barry delves into the 1918 influenza pandemic, he draws on his extensive background as a historian and advisor on pandemic policy to craft a detailed narrative that goes beyond mere dates and statistics. You gain insight into how the deadly virus spread, the intersection of science and politics, and the crucial role of transparency in public trust during health crises. The book’s chapters vividly recount outbreaks in army camps and cities, offering you a sobering view of epidemic management lessons still relevant today. If you seek to understand not just the pandemic itself but the broader societal impacts and responses, this book speaks directly to you.

#1 New York Times Bestseller
National Academies of Science Outstanding Book
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Best for personalized containment plans
This AI-created book on infectious disease containment is tailored to your background and goals. You share your experience, specific interests, and the challenges you face, and the book focuses on the containment methods most relevant to you. Personalizing the content helps you avoid generic information and gain focused knowledge that fits your unique needs. This approach makes learning more efficient and applicable, ensuring you get exactly what you want to know about infectious disease control.
2025·50-300 pages·Infectious Diseases, Outbreak Control, Transmission Dynamics, Public Health, Containment Methods

This tailored book explores proven strategies for infectious disease containment and control, focusing on your unique background and interests. It covers essential topics such as outbreak investigation, transmission dynamics, and intervention methods, all tailored to match your skill level and specific goals. By integrating widely validated knowledge with your personal objectives, it reveals how to efficiently analyze and respond to infectious threats. The book offers a personalized learning experience that examines real-world applications of containment practices and public health measures. It emphasizes the science behind infection control while addressing challenges relevant to your context, making complex concepts approachable and directly useful for your needs.

Tailored Book
Containment Expertise
3,000+ Books Created
Best for zoonotic disease insights
Kaleigh Rogers, a reporter known for her coverage of politics, technology, and science, highlights how "Spillover is a fantastic book" among infectious disease titles she recommends. Her endorsement reflects a deep appreciation for the book’s vivid storytelling and scientific insight, which helped her understand the complexities behind pandemics like COVID-19. This personal connection to the material underscores why so many readers have found value in Quammen’s exploration. Additionally, The Seattle Times praises Quammen as "one of the best science writers," likening the book to "The Hot Zone" for its gripping narrative, further affirming its impact on both experts and general readers alike.
KR

Recommended by Kaleigh Rogers

Reporter covering politics, tech, and science

@rachsyme Spillover is a fantastic book though. I'd also recommend Pandemic and/or The Fever by @son... (from X)

What if everything you thought you knew about disease outbreaks was missing a crucial piece? David Quammen, a seasoned science writer and National Geographic contributor, takes you on a global journey revealing how viruses leap from animals to humans in a process called spillover. You’ll explore gripping fieldwork chapters like netting bats in China and tracking gorillas in the Congo, gaining insight into the origins of Ebola, SARS, and more. This book lays bare the interconnectedness of ecosystems and pandemics, making it an eye-opening read for anyone interested in how infectious diseases emerge and spread.

New York Times Book Review Notable Book
Booklist Top 10 Science Book 2012
Daily Beast Top 11 Book 2012
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Best for pandemic response analysis
Arnold Schwarzenegger, actor and former governor of California, lends significant weight to this book's credibility with his endorsement, reflecting a broad public recognition of its importance. His experience in leadership during crises aligns with the book's examination of pandemic response failures and heroic efforts. Alongside him, Laura McInerney highlights the compelling character of a public health official whose insights were repeatedly overlooked, underscoring the book’s focus on the human elements in infectious disease management. Together, their perspectives underscore why this story resonates beyond specialized circles, offering valuable lessons about the complexity of handling a pandemic.
LM

Recommended by Laura McInerney

Co-Founder of TeacherTapp; education and polling expert

@langtrygirl It’s a really good book. You’ll love one character: a little public health woman, around 40, who was completely correct about it all and kept being ignored. I almost want this as a tattoo: (from X)

2021·320 pages·Infectious Diseases, Epidemic, Contagious Disease, Infectious Disease, Pandemic Response

Michael Lewis, known for his sharp storytelling in books like "Moneyball" and "The Big Short," steps into the public health arena with The Premonition, exploring the tangled response to the COVID-19 pandemic. You’ll discover the gripping narratives of a few determined scientists and public health officials who challenged official complacency, revealing systemic blind spots in American infectious disease preparedness. Specific chapters dive into grassroots efforts and the clash between data-driven insight and political denial. If you want a vivid, behind-the-scenes look at pandemic response and the human resolve behind it, this book offers a clear-eyed view, though it’s less about technical medical detail and more about the social and organizational dynamics at play.

New York Times Bestseller
American Scientist Science Book of 2021
Bloomberg Best Book of 2021
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Best for Ebola outbreak details
Elizabeth Kolbert, Pulitzer Prize–winning author of The Sixth Extinction, praises this book as a gripping thriller based on true events, capturing the terrifying reality of the 2013–2014 Ebola outbreak. She highlights how Preston’s storytelling not only informs but unsettles, bringing to light the urgent challenges faced by doctors and scientists during the epidemic. Her endorsement aligns with the widespread acclaim this book has garnered among those seeking a deep understanding of infectious diseases and the threats they pose globally.

Recommended by Elizabeth Kolbert

Pulitzer Prize–winning author of The Sixth Extinction

Crisis in the Red Zone reads like a thriller. That the story it tells is all true makes it all more terrifying, and there’s no one who could tell it better than Richard Preston. (from Amazon)

What if everything you knew about viral outbreaks was incomplete? Richard Preston, an acclaimed author with a history of chronicling deadly pathogens, dives into the 2013–2014 Ebola epidemic with meticulous detail and narrative urgency. You get a vivid sense of the human and scientific drama behind the scenes—from healthcare workers risking everything to the ethical dilemmas of distributing experimental treatments. The book also explores how modern connectivity and environmental change have set the stage for viruses to spread faster and mutate more dangerously. If you want to understand not just the outbreak itself but the broader implications for emerging infectious diseases, this book offers detailed, gripping insights.

New York Times Bestseller
View on Amazon
Best for rapid response plans
This AI-created book on pandemic response is tailored to your specific goals and background. By sharing your experience level and the aspects of pandemic management you want to focus on, you receive a book that matches your interests and offers practical, relevant guidance. Unlike generic resources, this personalized book helps you concentrate on what matters most to you for effective and timely action in pandemic situations.
2025·50-300 pages·Infectious Diseases, Pandemic Management, Outbreak Control, Transmission Dynamics, Response Planning

This tailored book offers a focused exploration of pandemic management, designed specifically to match your background and goals. It examines step-by-step approaches to navigating pandemic challenges, blending widely recognized knowledge with insights that resonate with your unique situation. By concentrating on your interests, it reveals how to efficiently respond to outbreaks, understand transmission dynamics, and implement practical measures that align with your personal circumstances. This personalized guide brings together reader-validated knowledge, enabling you to grasp essential concepts without wading through unrelated materials. The content examines pandemic response from multiple angles, providing a clear pathway to informed decision-making and effective action.

Tailored Guide
Pandemic Response Insights
3,000+ Custom Books Made
Best for Lyme disease investigations
Grrl Scientist, an evolutionary ecologist and science writer, highlights this book with enthusiasm, calling it a "WHOA!! must-read book! Lyme". Her expertise in biology and ecology adds weight to her recommendation, especially given Lyme disease's complexity and ecological aspects. Her excitement reflects the book's ability to challenge conventional narratives and offer fresh perspectives, making it a compelling choice for those curious about both the science and the hidden histories behind this pervasive infectious disease.
GS

Recommended by Grrl Scientist

Evolutionary ecologist and science writer

WHOA!! must-read book! Lyme (from X)

2019·336 pages·Infectious Diseases, Infectious Disease, Biological Weapons, Microbiology, Epidemiology

Drawing from her personal ordeal with Lyme disease and her expertise as a science writer, Kris Newby unravels the tangled and often concealed history of this illness. You learn not only about the biology of the disease and its discoverer Willy Burgdorfer but also the controversial connections to Cold War biological weapons programs and the challenges in diagnosing and treating chronic Lyme. The book offers detailed investigative narratives including interviews with microbiologists and biosecurity experts, making it valuable if you want a deeper understanding beyond typical medical texts. If you seek a gripping exploration that questions official accounts and reveals systemic medical and governmental hesitancies, this book will engage you, though it might be less suitable if you prefer purely clinical guides.

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Best for epidemiology modeling experts
This book stands out in infectious diseases for integrating mathematical frameworks with epidemiological data to analyze viral, bacterial, protozoan, and helminth infections. It offers a structured approach to understanding disease dynamics, dividing the content between microparasites and macroparasites, and advancing from intuitive models to sophisticated tools for public health planning. Its thorough methodology addresses critical diseases and emerging infections, making it valuable for professionals seeking to evaluate or design disease control strategies within infectious diseases.
1991·766 pages·Infectious Disease, Infectious Diseases, Epidemiology, Mathematical Modeling, Public Health

What started as an effort to unify scattered research, Roy M. Anderson and Robert M. May crafted a detailed exploration of infectious diseases, focusing on their dynamic interaction with host populations. You’ll learn to understand how mathematical modeling illuminates the spread and control of viruses, bacteria, protozoans, and helminths, with practical implications for public health strategies against diseases like malaria and AIDS. The book divides its focus between microparasites and macroparasites, gradually building from simple to complex models that sharpen your analytical approach to epidemiology. If you’re involved in public health, epidemiology, or infectious disease research, this book offers a rigorous framework rather than quick fixes.

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Best for pandemic thriller readers
Bobby Akart delivers up-all-night thrillers to readers in 245 countries and territories worldwide. He has sold over one million books across fiction and nonfiction genres, including over forty international bestsellers. This proven track record and extensive reach give "Pandemic: Level 6" a unique authority in portraying infectious disease threats. Akart’s ability to blend thrilling narrative with factual underpinnings offers you a gripping and insightful look at pandemic scenarios shaped by both natural evolution and human interference.
Pandemic: Level 6 book cover

by Bobby Akart··You?

2017·304 pages·Infectious Diseases, Epidemiology, Pandemics, Bioterrorism, Public Health

When Bobby Akart crafted "Pandemic: Level 6," he tapped into his flair for up-all-night thrillers to explore the terrifying progression of pandemics from their subtle beginnings to global devastation. You get drawn into a fictional yet scientifically grounded world where infectious diseases evolve and spread, amplified by the menace of bioterrorism. The book offers insights into epidemic dynamics, social distancing impacts, and the human desperation in a post-apocalyptic setting, especially evident in chapters detailing the genetically modified plague. If you're drawn to narratives that blend medical knowledge with suspenseful storytelling, this book will keep you engaged while expanding your understanding of pandemic risks and responses.

International Bestseller
Adapted for university course study
View on Amazon
Best for historical epidemiology fans
Steven Johnson’s The Ghost Map offers a vivid historical lens on infectious diseases, focusing on a pivotal cholera outbreak in 1854 London. The book blends scientific inquiry with urban development, illustrating how Dr. John Snow’s mapping of cholera cases changed public health and city planning forever. Readers interested in infectious diseases and their societal impact will find this narrative both engaging and informative, as it addresses how outbreaks intersect with infrastructure and human behavior. This work stands out for its multidisciplinary approach, making it relevant to those seeking to understand the roots of modern epidemiology within the broader medical specialties category.

Steven Johnson challenges the conventional wisdom that historical epidemics are mere medical footnotes by weaving together the rise of modern cities, the scientific method, and infectious disease spread in 1854 London. Through the gripping account of Dr. John Snow's investigation of a cholera outbreak, you gain insight into early epidemiology, urban infrastructure challenges, and how data visualization shaped public health. Chapters detailing Snow's pioneering map tracing transmissions highlight the tangible impact of empirical science on society. If you're intrigued by how science and urban planning intersect in disease control, this book offers a focused, narrative-driven exploration rather than a technical manual.

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Best for malaria historical context
Bill Gates, co-founder of Microsoft and a leading philanthropist in global health, recommends this book, underscoring its importance in understanding malaria's enduring challenge. His experience investing billions in infectious disease eradication lends weight to his endorsement, signaling that this book offers valuable historical and epidemiological perspectives that inform ongoing efforts. Alongside him, Sue Desmondhellmann, former CEO of the Gates Foundation, highlights the book's skillful historical context, making it a compelling read for those interested in how malaria shapes public health narratives around the world.
SD

Recommended by Sue Desmondhellmann

Former CEO of Gates Foundation

Here’s one for your summer reading list: The Fever by Sonia Shah is a terrific book that puts malaria work into historic context—one of my favorite genres of writing. (from X)

Unlike most infectious diseases books that focus narrowly on medical details, Sonia Shah's decades of science journalism led to a rich narrative exploring malaria's deep-rooted impact on human history and society. You learn about the disease's persistent grip through historical events like the Panama Canal construction and the Industrial Revolution, gaining insight into why malaria remains a formidable foe despite a century of prevention efforts. The book blends investigative reporting from locations like Malawi and India with an understanding of how human hopes and failures have shaped the fight against malaria. If you want a broader view beyond biology—combining history, politics, and public health—this book is for you, though it may be less suited if you're seeking purely clinical analysis.

Long-listed for Royal Society's Winton Prize
Featured on TED with 1 million+ views
Praised by New York Times and Wall Street Journal
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Conclusion

These 10 infectious diseases books reveal clear themes: the power of storytelling to illuminate complex science, the importance of historical lessons in shaping current responses, and the critical role of expert insight in guiding public health strategies. If you prefer proven methods grounded in epidemiology, start with Infectious Diseases of Humans and The Great Influenza. For validated approaches blending narrative and science, combine The Hot Zone with Spillover.

For those looking to deepen your understanding with content tailored precisely to your interests—whether clinical, historical, or policy-focused—you might consider creating a personalized Infectious Diseases book. This lets you integrate these widely adopted approaches with your unique learning objectives, maximizing value.

These widely-adopted approaches have helped many succeed in mastering infectious diseases knowledge, offering you a reliable path through an ever-evolving field.

Frequently Asked Questions

I'm overwhelmed by choice – which book should I start with?

Start with The Hot Zone for an engaging introduction to viral outbreaks, or The Great Influenza to understand pandemic history. Both offer accessible narratives that ground you in key infectious disease concepts.

Are these books too advanced for someone new to Infectious Diseases?

Not at all. Titles like The Fever and The Ghost Map use storytelling to explain complex topics, making them approachable for newcomers while still offering depth for experienced readers.

What's the best order to read these books?

Begin with gripping narratives like The Hot Zone and Spillover, then move to analytical works such as Infectious Diseases of Humans. Finish with recent pandemic-focused books like The Premonition for current insights.

Should I start with the newest book or a classic?

Both have value. Classics like The Great Influenza provide foundational history, while newer books like The Premonition offer fresh perspectives on recent pandemics and response challenges.

Can I skip around or do I need to read them cover to cover?

You can skip around. Many of these books stand alone, so pick topics or diseases that interest you most without needing to follow a strict sequence.

How can I get infectious diseases knowledge tailored to my specific needs?

While these expert-recommended books offer broad insights, personalized Infectious Diseases books combine proven methods with your unique background and goals. Consider creating your own tailored book for focused, efficient learning.

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