8 New Pain Medicine Books Reshaping the Field in 2025

Discover authoritative Pain Medicine Books by Laxmaiah Manchikanti, Annette Phillips, and others, featuring new insights and practical strategies for 2025

Updated on June 25, 2025
We may earn commissions for purchases made via this page

The Pain Medicine landscape has shifted profoundly in 2024, with emerging regenerative techniques and holistic approaches gaining momentum. As the field embraces more personalized and integrative methods, staying current with these innovations is crucial for practitioners and patients alike. The evolving interplay between neuroscience, interventional procedures, and behavioral science is reshaping how pain is understood and managed.

These 2025 Pain Medicine books come from authors deeply embedded in the discipline, offering perspectives grounded in decades of clinical experience and cutting-edge research. From Laxmaiah Manchikanti's exploration of regenerative therapies to Annette Phillips' holistic pain relief strategies, these texts reflect the diverse and forward-thinking approaches shaping pain care today.

While these books provide detailed insights into the latest developments, if you want content tailored precisely to your background and pain management goals, consider creating a personalized Pain Medicine book. This option builds on these trends, delivering focused knowledge that fits your unique needs and keeps you ahead in 2025.

Regenerative medicine is reshaping interventional pain management, and this book dives into its latest developments with precision. Covering minimally invasive procedures like precision needle placement and nerve ablation, alongside surgical options such as laser diskectomy and spinal cord stimulators, it offers a thorough framework for treating chronic and intractable pain. The authors compile global expert contributions to present evidence-based applications across spinal, neurological, and musculoskeletal pain. This text addresses the growing need for integrating regenerative approaches into pain medicine, making it a valuable resource for physicians seeking to expand their treatment arsenal with scientifically supported techniques.
Essentials of Regenerative Medicine in Interventional Pain Management book cover

by Laxmaiah Manchikanti, Annu Navani, Sairam Atluri, Mahendra Sanapati·You?

2024·637 pages·Pain Management, Pain Medicine, Pain, Regenerative Medicine, Interventional Techniques

What happens when decades of expertise in interventional pain management meet regenerative medicine? Laxmaiah Manchikanti and his coauthors present a detailed examination of minimally invasive procedures combined with regenerative techniques for chronic pain relief. You’ll find nuanced discussions on needle placement, ablation, and emerging therapies supported by evidence, alongside chapters that cover anatomy and procedural complications. This book suits physicians aiming to integrate regenerative methods into their pain management practice, especially those dealing with spinal, neurological, and musculoskeletal pain. If your focus is on practical application backed by global expert insights, this book offers a solid foundation without overstating its reach.

View on Amazon
Best for holistic pain relief seekers
Annette Phillips brings a rare combination of clinical expertise and personal experience to this book, shaped by 35 years in hospital nursing alongside her own journey with chronic pain. Her deep understanding of both the science and lived reality of pain informs a compassionate, practical guide to holistic relief. Driven by a passion to offer alternatives free from addiction or side effects, Phillips translates complex medical insights into accessible strategies that anyone dealing with persistent pain can apply.
2024·156 pages·Pain Medicine, Pain Management, Holistic, Physical Therapy, Nutrition

Annette Phillips draws on her 35 years of hospital nursing and personal battles with chronic pain to deliver a thoughtful exploration of non-pharmaceutical pain relief. You’ll gain practical knowledge about the biology of pain, simple exercises, dietary advice, and both ancient and modern techniques that sidestep the risks of addiction and side effects. The book’s chapters demystify common myths and guide you through creating a personalized pain management plan, empowering you to advocate for your own health in often complex medical systems. This is ideal if you’re seeking holistic, sustainable alternatives rather than quick pharmaceutical fixes.

View on Amazon
Best for custom pain treatment plans
This AI-created book on pain medicine is designed based on your specific interests and goals for 2025. By sharing your background and the pain management topics that matter most to you, you receive a tailored exploration of the newest breakthroughs and research. This focused approach helps you navigate an evolving field with clarity and confidence, without wading through unrelated material.
2025·50-300 pages·Pain Medicine, Pain Management, Regenerative Techniques, Pharmacology Advances, Interventional Procedures

This tailored book explores the latest developments in pain medicine as of 2025, focusing on breakthrough treatments and emerging research that shape modern pain management. It examines cutting-edge discoveries in pharmacology, regenerative techniques, and integrative approaches, providing a personalized learning experience that matches your background and goals. The content delves into innovative therapies, advances in interventional procedures, and the evolving understanding of pain neuroscience.

Tailored Content
Regenerative Insights
1,000+ Happy Readers
Best for clinicians updating multimodal strategies
This book stands out in pain medicine by addressing the full spectrum of pain management, from acute surgical pain to chronic conditions, through the lens of recent advancements. It explores a personalized, multimodal approach incorporating pharmacological, psychological, and integrative methods, reflecting the latest trends in precision medicine. Offering a broad yet detailed survey of emerging strategies, it serves as an important resource for clinicians aiming to refine their practice and improve patient care in the evolving landscape of pain management.
Pain Management - From Acute to Chronic and Beyond (Pharmaceutical Science) book cover

by Theodoros Aslanidis, Christos Nouris·You?

2024·344 pages·Pain Medicine, Pain Management, Pharmacotherapy, Psychotherapy, Integrative Treatments

Theodoros Aslanidis and Christos Nouris bring a fresh perspective to pain management, reflecting their deep engagement with both surgical and chronic pain challenges. This book drills down into the latest treatment modalities, blending pharmacotherapy, psychotherapy, and integrative approaches into a personalized framework. You’ll find detailed discussions on multimodal interventions and the evolving role of precision medicine, particularly useful for clinicians navigating complex pain cases. While the text covers a broad spectrum — from acute postoperative pain to persistent chronic conditions — it’s especially suited for healthcare professionals seeking to update their practice with the newest, evidence-informed therapies.

View on Amazon
Best for chronic pain self-management
This guide to pain relief from Mayo Clinic merges clinical expertise with accessible explanations of chronic pain's complexities, emphasizing the brain's role and behavioral factors in pain experience. It introduces the take-charge pain management program that has supported thousands over 40 years, refreshed here with the latest research and practical advice. The authors focus on helping you regain function and embrace a balanced, active life despite pain, providing clear insights into medications, therapies, and rehabilitation options. If you seek to understand and manage chronic pain beyond conventional treatments, this book offers a thoughtful, science-based roadmap.
2024·192 pages·Pain Management, Chronic Pain, Pain Medicine, Pain, Brain Science

Drawing from decades of expertise at Mayo Clinic's Pain Rehabilitation Center, Wesley P. Gilliam Ph.D. and Bruce Sutor M.D. offer a fresh perspective on chronic pain that goes beyond pills and procedures. You’ll explore how pain is processed in the brain, uncover the powerful influence of your beliefs and behaviors on pain perception, and learn why shifting focus from pain itself to living well can alter your experience profoundly. The book lays out practical methods to regain physical function and balance, emphasizing exercise and moderation as pillars of sustainable relief. If you’re facing persistent pain and want clear, science-backed guidance on managing it without surrendering your life, this guide speaks directly to you.

View on Amazon
Best for mastering pain intervention skills
The Pain Procedure Handbook offers a clear, structured pathway to mastering complex pain interventions, setting itself apart with a milestone-based framework that guides you from beginner to advanced skills. It focuses on practical steps necessary for nerve blocks and injections, supported by helpful imaging and safety insights. Ideal for medical students and clinicians in pain medicine, anesthesiology, and rehabilitation, this book addresses the need for a concise procedural reference rather than an exhaustive theoretical text. Its approach helps you build competence in pain procedures efficiently and confidently.
The Pain Procedure Handbook: A Milestones Approach book cover

by Trent Emerick, Scott Brancolini, Michael E. Farrell II, Ajay Wasan·You?

2023·258 pages·Pain Medicine, Pain Management, Medical Procedure, Nerve Blocks, Injection Techniques

The Pain Procedure Handbook emerges from the combined clinical expertise of Trent Emerick, Scott Brancolini, Michael E. Farrell II, and Ajay Wasan, all seasoned pain medicine specialists. The authors focus on a milestone-based approach to mastering complex pain procedures, breaking down each intervention into progressive skill sets tailored to novice through advanced practitioners. You’ll gain clear guidance on performing nerve blocks and injections safely, supported by detailed imaging and practical safety tips. This book suits medical students, residents, and clinicians keen to refine procedural proficiency in chronic and acute pain treatment rather than deep theoretical explorations.

View on Amazon
Best for custom knowledge plans
This AI-created book on pain medicine is tailored to your background and specific interests in emerging developments. By sharing your skill level and the pain management topics you want to explore, you receive a book that focuses on the most relevant and forward-thinking insights shaping the field in 2025. This personalized approach means you get exactly the knowledge you need to prepare for the evolving trends without sifting through unrelated information.
2025·50-300 pages·Pain Medicine, Pain Management, Emerging Research, Regenerative Therapies, Neuroscience Advances

This personalized book explores future-ready insights in pain medicine, focusing on emerging trends and discoveries relevant to 2025 and beyond. It examines the evolving landscape of pain management through a lens tailored to your background and interests, allowing you to engage deeply with the newest research and innovations. From advances in regenerative therapies to integrative approaches and neuroscience breakthroughs, the content is customized to match your specific goals and expertise. By concentrating on your unique areas of curiosity and professional needs, this tailored guide reveals how pain care is expected to develop, equipping you to stay ahead of changes and refine your practice based on personalized, relevant knowledge.

Tailored Content
Emerging Research
1,000+ Happy Readers
Best for evidence-based chronic pain care
The Cambridge Handbook of Pain Medicine offers a timely and practical overview of the latest developments in chronic pain management. This handbook lays out detailed information on pain types and symptoms, alongside diverse management strategies including medication, physical therapy, and psychological treatments. It is designed to equip healthcare professionals—from pain physicians to nurse anesthetists—with the knowledge necessary to improve patient outcomes and reduce risks like opioid dependence. Covering major chronic pain conditions and integrating current evidence, this work serves as a trusted clinical reference for those advancing their expertise in pain medicine.
2023·382 pages·Pain Medicine, Pain, Pain Management, Chronic Pain, Medication

Drawing from his extensive experience in anesthesiology and pain medicine, Omar Viswanath crafted this handbook to address the rapidly evolving landscape of chronic pain management. You gain detailed insights into the types of chronic pain affecting areas like the head, neck, spine, and extremities, along with the latest evidence-based techniques for treatment including medication, physical therapy, and psychological approaches. The book also highlights ways to mitigate opioid dependence while improving patient quality of life, making it an essential guide for clinicians seeking updated clinical knowledge. If you’re involved in pain medicine or preparing for board certifications, this resource offers targeted information grounded in current practice standards.

View on Amazon
Best for practical clinical pain solutions
Baburao Doddapaneni is a renowned pain management specialist with extensive experience in treating various pain conditions. His expertise spans traditional and alternative therapies, reflecting a commitment to improving patient outcomes. This revised edition reflects his comprehensive approach, offering medical professionals practical tools and clear guidance to address pain from acute episodes to complex chronic conditions.
2023·180 pages·Pain Management, Pain Medicine, Pain, Pharmacology, Chronic Pain

Baburao Doddapaneni's decades of clinical experience led to this revised manual, designed to equip medical professionals with practical methods for managing a broad spectrum of pain conditions. You’ll find detailed chapters addressing chronic headaches, fibromyalgia, joint pain, and low back pain, each offering clear explanations of analgesic roles and opioid use. The book balances scientific theory with evidence-based treatment plans, supported by instructive graphics, making complex pain management concepts accessible. If you’re involved in primary care or specialized medicine, this manual offers concrete insights to enhance your approach to both acute and chronic pain treatment.

View on Amazon
Best for intractable pain diagnosis and care
Unlike many texts that broadly cover pain management, this handbook zeroes in on a subgroup of chronic pain patients whose central nervous system changes lead to constant, debilitating discomfort. The book explores how this persistent pain triggers serious complications across multiple bodily systems, a connection often missed in clinical practice. It offers practical recognition and treatment guidance aimed at practitioners, patients, and families confronting this severe condition. By addressing this under-recognized malady, the handbook fills a critical gap in pain medicine and supports better health outcomes for a vulnerable patient population.
2023·97 pages·Pain Medicine, Pain Management, Pain, Chronic Pain, Central Nervous System

MPH Tennant DrPh MD Forest brings clinical insight to a largely overlooked area in pain medicine—patients suffering from biologic changes causing relentless, intractable pain. This handbook guides you through recognizing this distinct chronic pain syndrome and its widespread effects on cardiovascular, endocrine, cerebral, and gastrointestinal health. You’ll gain a clearer understanding of the physiological stress this condition imposes and practical approaches to treatment that can extend quality and length of life. The book suits medical practitioners seeking guidance on diagnosing and managing this complex pain subset, as well as patients and families aiming to better comprehend the disorder's gravity and treatment options.

View on Amazon

Stay Ahead: Get Your Custom 2025 Pain Medicine Guide

Access the latest Pain Medicine strategies without endless reading.

Targeted insights fast
Updated research focus
Personalized learning path

Leading pain medicine practitioners trust tailored learning in this field

2025 Pain Medicine Revolution
Tomorrow's Pain Care Blueprint
Pain Medicine Trend Secrets
Pain Medicine Action System

Conclusion

The collection of Pain Medicine books published recently highlights several key themes: the integration of regenerative medicine into interventional practices, the rise of holistic and multidisciplinary approaches, and a sharpened focus on managing complex chronic pain conditions including intractable syndromes. These works collectively suggest a future where pain management is more personalized, evidence-based, and mindful of both biological and psychological dimensions.

If staying ahead of clinical trends is your priority, starting with "Essentials of Regenerative Medicine in Interventional Pain Management" and "Pain Management" offers a strong foundation. For practical application, pairing "The Pain Procedure Handbook" with "Dr. D’s Pain Treatment Manual" equips practitioners with actionable skills. Meanwhile, patients and advocates may find "Mayo Clinic Guide to Pain Relief" and "Alternative Pain Relief Methods" especially empowering.

Alternatively, you can create a personalized Pain Medicine book to apply the newest strategies and latest research directly to your situation. These books offer the most current 2025 insights and can help you stay ahead of the curve in this rapidly advancing field.

Frequently Asked Questions

I'm overwhelmed by choice – which book should I start with?

Start with the "Mayo Clinic Guide to Pain Relief" if you're looking for a clear, patient-friendly overview. For clinicians, "Essentials of Regenerative Medicine in Interventional Pain Management" offers foundational knowledge on cutting-edge therapies.

Are these books too advanced for someone new to Pain Medicine?

Not at all. Some, like "Alternative Pain Relief Methods," are accessible for beginners, while others provide deeper dives suited for professionals expanding their expertise.

What's the best order to read these books?

Begin with general overviews such as "Pain Management" before moving to specialized texts like "The Pain Procedure Handbook" for procedural skills and "Handbook for Intractable Pain" for complex cases.

Should I start with the newest book or a classic?

These 2025 publications reflect the latest thinking, so starting with them ensures you’re aligned with current practices rather than older conventions.

Which books focus more on theory vs. practical application?

"Pain Management" and "Cambridge Handbook of Pain Medicine" emphasize theory and evidence, whereas "The Pain Procedure Handbook" and "Dr. D's Pain Treatment Manual" prioritize practical clinical techniques.

How can I get Pain Medicine insights tailored to my needs without reading all these books?

Great question! While these expert books provide solid knowledge, you can create a personalized Pain Medicine book tailored to your experience, goals, and interests, keeping your learning focused and up-to-date.

📚 Love this book list?

Help fellow book lovers discover great books, share this curated list with others!