10 Best-Selling Human Brain Books Millions Trust

Explore Human Brain Books recommended by Daniel Gilbert, Kirk Borne, Tomasz Tunguz—experts sharing proven, best-selling insights

Kirk Borne
Tomasz Tunguz
Preston Pysh
Maria Shriver
Updated on June 27, 2025
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When millions of readers and top experts agree on a collection of books, it's worth paying attention. The human brain fascinates us all, from scientists to curious minds, because understanding it unlocks doors to mental health, emotional well-being, and cognitive performance. These 10 best-selling books have not only captivated a wide audience but have also earned endorsements from specialists who bridge neuroscience, psychology, and even spirituality.

Take Daniel Gilbert, a Harvard psychology professor, who praises How Emotions Are Made for reshaping how we understand feelings. Data scientist Kirk Borne highlights the same book's crucial insights for advancing AI, while investor Tomasz Tunguz recognizes its relevance in cognitive science. Meanwhile, neurologist David Perlmutter and biohacker Dave Asprey champion works that explore brain nutrition and energy optimization.

These popular books offer proven frameworks, but if you're seeking something built precisely for your unique brain needs and goals, consider creating a personalized Human Brain book. This tailored approach combines validated methods with your personal background for focused learning and practical application.

Best for understanding emotion science
Tomasz Tunguz, General Partner at Theory Ventures, offers a notable endorsement of this book, underscoring its relevance for understanding the human brain's role in emotion construction. With his background in venture investing and technology, Tunguz's interest highlights the book’s value beyond psychology, resonating with innovators exploring AI and cognitive science. Additionally, Kirk Borne, Principal Data Scientist at Booz Allen and a recognized data science influencer, emphasizes the importance of this work in the context of advancing artificial intelligence, noting its critical insights into emotion science. Their combined endorsements reflect why this book is highly regarded by experts bridging neuroscience and emerging technologies.

Recommended by Daniel Gilbert

Professor of Psychology, Harvard University

A brilliant and original book on the science of emotion, by the deepest thinker about this topic since Darwin. (from Amazon)

Lisa Feldman Barrett, a University Distinguished Professor of Psychology, challenges the traditional idea that emotions are fixed, automatic responses hardwired in the brain. Instead, she presents research showing emotions are constructed through a dynamic interplay of brain, body, and cultural context. You’ll gain insight into how this perspective reshapes understanding in psychology, medicine, and even law, with chapters examining the neuroscience behind emotion construction and its implications for society. This book suits anyone curious about human behavior beyond simple feelings, especially those interested in the brain’s complexity and cultural influence on emotions.

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Best for brain plasticity insights
Preston Pysh, an aerospace engineer and globally ranked podcast host, highlights this book's appeal beyond typical neuroscience circles. His straightforward comment, "Yes, I’ve read it. Very fascinating book," reflects a genuine intrigue sparked by the book’s exploration of brain adaptability. Pysh’s engagement with this work underscores its relevance to anyone curious about the brain’s capabilities and the science shaking long-held assumptions about human potential.
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Recommended by Preston Pysh

Aerospace engineer and investor, podcast host

@RolandDPT @Breedlove22 Yes, I’ve read it. Very fascinating book. (from X)

2007·448 pages·Human Brain, Neuroscience, Brain Plasticity, Cognitive Science, Brain Injury

Norman Doidge, a psychiatrist and psychoanalyst with decades on the psychiatry faculties at Columbia and Toronto, challenges the old belief that the brain is fixed and unchangeable. Through vivid case studies—like a woman born with half a brain that rewired itself and stroke patients relearning speech—you explore the science of neuroplasticity and its surprising implications. You'll grasp how brain injuries, learning disorders, and even lifelong traits can be reshaped, gaining insight into the brain's adaptability and potential. This book suits anyone curious about neuroscience’s real-life impact, especially those intrigued by the brain's capacity for healing and transformation.

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Best for personal brain mastery plans
This custom AI book on brain mastery is created based on your unique challenges and interests. You share your background, skill level, and specific brain-related goals, and the book is crafted to focus on methods that work best for you. By combining proven brain techniques with your personal context, it offers a learning experience that feels relevant and engaging, helping you unlock your cognitive potential efficiently.
2025·50-300 pages·Human Brain, Brain Function, Cognitive Techniques, Neuroplasticity, Mental Exercises

This tailored book explores the fascinating landscape of human brain mastery by focusing on battle-tested methods adapted to your unique challenges. It combines popular, reader-validated knowledge with your specific interests, providing a clear pathway to understanding how your brain functions and how you can enhance its capabilities. The book examines essential cognitive techniques, neuroscience insights, and practical mental exercises, all matched to your background and goals. By personalizing content to your needs, it reveals how to unlock proven brain methods that millions have found valuable, helping you grasp and apply concepts that truly resonate with your learning journey.

Tailored Blueprint
Cognitive Enhancement
3,000+ Books Created
Best for biohacking brain energy
David Perlmutter, a board-certified neurologist and #1 New York Times bestselling author, praises this book for its masterful use of cutting-edge neuroscience combined with personal experience. He highlights how Dave Asprey’s approachable guide fulfills its promise to protect and enhance brain function, making it a standout resource for anyone seeking sharper mental performance. This endorsement resonates with many readers who’ve found the two-week biohacking program practical and effective. Alongside Perlmutter, Steven Masley notes how simple daily choices can significantly boost focus, mood, and energy, reinforcing the book’s appeal for those wanting tangible brain health improvements.

Recommended by David Perlmutter

Board-certified neurologist, #1 NYT bestselling author

Dave Asprey has masterfully utilized leading edge neuroscience as well as his extensive personal experience to create a user-friendly guide that will clearly fulfill its promise to protect, restore, and enhance brain function. Head Strong is a tour de force. (from Amazon)

2017·352 pages·Human Brain, Neuroscience, Biohacking, Brain Health, Mitochondria

After years of working with top doctors and scientists, Dave Asprey developed a plan to unlock hidden brain energy with practical lifestyle changes. You learn how to fuel your brain for peak performance, cut out nutritional and environmental factors that slow you down, and boost mitochondrial function to sharpen focus and reduce cravings. Asprey also dives into promoting neuron growth and calming inflammation to help you think faster and stay mentally resilient. This book suits anyone looking to enhance cognitive function through biohacking techniques rather than traditional methods, offering a clear two-week program that integrates diet, exercise, supplements, and environment optimization.

New York Times Bestseller
Author of 4+ bestselling books
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Best for brain nutrition strategies
Maria Shriver, an American journalist and activist, highlights the importance of diet in brain health, emphasizing how Dr. Perlmutter's work connects what you eat with your mind's well-being. She reflects, "If we want to care for our minds, then we have to be mindful about what we eat. Dr. Perlmutter under..." This perspective aligns with the widespread reader interest in Grain Brain and underscores why this book continues to resonate. Following her endorsement, Daniel Amen, founder of Amen Clinics, praises the book as life-changing, reinforcing its impact on brain and body health. Together, their insights invite you to reconsider your dietary habits as a pathway to sharper cognitive function.
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Recommended by Maria Shriver

American journalist and activist

If we want to care for our minds, then we have to be mindful about what we eat. Dr. Perlmutter understands the connection between diet and brain health, and this revised edition of Grain Brain teaches us that simple lifestyle changes can make a world of difference. (from Amazon)

2018·384 pages·Human Brain, Diet, Neurology, Nutrition, Inflammation

Drawing from his expertise as a board-certified neurologist and nutrition fellow, Dr. David Perlmutter challenges conventional wisdom about carbohydrates and brain health. He explains how common foods like wheat and sugar may contribute to inflammation linked to neurological conditions such as dementia and anxiety. The book offers a detailed 4-week plan emphasizing a high-fat, low-carb diet designed to improve cognitive function and reduce risk factors. You’ll find practical chapters on how statin drugs might affect memory and ways to promote brain cell growth regardless of age. This is a focused read for anyone curious about the dietary roots of brain disorders and natural approaches to cognitive wellness, though it may not suit those looking for broad neuroscience coverage.

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Best for tech impact on cognition
Nicholas Carr's "The Shallows" stands as a widely recognized examination of how digital technology influences your brain's functioning. This book draws on decades of cognitive science and cultural history to argue that the Internet is reshaping your ability to concentrate and think deeply. By weaving neuroscience discoveries with historical examples, it challenges you to reconsider the intellectual cost of our online lives. Whether you’re a student, professional, or simply curious about the mind, this work offers a thoughtful perspective on the evolving relationship between human cognition and technology.
2010·288 pages·Human Brain, Cognitive Science, Neuroscience, Media Effects, Technology Impact

Nicholas Carr’s exploration confronts a pressing question: how is the Internet reshaping your brain? Drawing on neuroscience and intellectual history, he shows how digital technologies reroute neural pathways, shifting your thinking from deep reflection to rapid skimming. You’ll encounter vivid examples, like Nietzsche wrestling with a typewriter and Freud’s brain studies, which illustrate how tools have influenced cognition across centuries. This book suits anyone curious about how media transforms thought patterns, especially if you’re grappling with distractions or seeking to understand the cultural impact of technology.

Finalist for 2011 Pulitzer Prize
Finalist for 2011 PEN Center USA Award
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Best for custom cognitive plans
This AI-created book on cognitive enhancement is tailored to your skill level, interests, and goals for rapid mental improvement. You share your background and the specific brain functions you want to strengthen, and the book focuses on practical, step-by-step brain actions designed to create noticeable changes within 30 days. Personalizing your brain training ensures learning is efficient and engaging, avoiding generic advice and honing in on what will work best for you.
2025·50-300 pages·Human Brain, Cognitive Enhancement, Neuroplasticity, Memory Training, Focus Techniques

This personalized 30-Day Brain Boost System explores targeted brain exercises and cognitive actions designed to deliver noticeable mental improvements within one month. The book combines widely validated neuroscience insights with your unique background and goals, creating a tailored journey that focuses on maximizing your cognitive gains efficiently. It carefully examines step-by-step brain activities that promote sharper thinking, better memory, and enhanced focus, all aligned with your interests and current knowledge level. By concentrating on what matters most to you, this book reveals how to accelerate brain performance through a customized, engaging approach that respects your personal pace and ambitions.

Tailored Content
Rapid Brain Gains
1,000+ Happy Readers
Best for neuroplasticity healing methods
Norman Doidge, M.D., a psychiatrist and psychoanalyst on faculty at Columbia University and the University of Toronto, brings his extensive clinical and research background to this exploration of neuroplasticity. Known for his New York Times bestselling work, he delves into how the brain can heal itself using natural energy forms like light and sound, challenging long-held beliefs about brain damage. His authoritative voice connects cutting-edge science to practical healing insights that anyone interested in brain health can appreciate.
2015·409 pages·Human Brain, Neuroplasticity, Brain Healing, Neurology, Cognitive Recovery

Norman Doidge's decades of expertise in psychiatry and psychoanalysis led him to explore the brain's remarkable capacity for healing through neuroplasticity. You learn how natural stimuli like light, sound, and movement can awaken your brain's own repair mechanisms, offering new hope for conditions once thought irreversible, such as strokes, chronic pain, and neurological disorders. The book walks you through detailed case studies and practical insights, showing how these noninvasive approaches foster recovery and improved brain function. If you're seeking to understand how the brain can adapt and heal beyond traditional medicine, this book offers clear scientific explanations grounded in real patient stories.

New York Times Bestseller
2015 Gold Nautilus Book Award
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Best for OCD self-treatment techniques
Brain Lock offers a distinctive contribution to understanding and managing obsessive-compulsive disorder by presenting a self-treatment approach that alters brain chemistry without medication. This method, developed by psychiatrist Jeffrey M. Schwartz, is built on a four-step behavioral therapy framework supported by patient case stories, making it accessible to those seeking alternatives to pharmaceuticals. The book addresses a complex mental health challenge by empowering individuals with tools to change their thought patterns and behaviors, providing a valuable resource for anyone impacted by OCD who wishes to regain control through proven psychological strategies.

Drawing from his expertise as a psychiatrist, Jeffrey M. Schwartz offers a unique approach to obsessive-compulsive disorder that focuses on changing brain chemistry without medication. The book lays out a four-step self-treatment method grounded in brain metabolic behavioral therapy, illustrated through real patient stories that make the process tangible and relatable. You’ll gain insight into how obsessive thoughts and compulsions can be addressed through mindful awareness and mental discipline, empowering you to take control of your behavior. This approach suits those who prefer drug-free options and want practical techniques to manage and reduce OCD symptoms on their own terms.

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Best for neuroscience of grief
Oprah Daily, an influential media publication known for curating thoughtful content on human experience, highlighted this book for its clear explanation of the confusion grief brings. They describe it as "a fascinating and comforting read" that helps you grasp why grief feels so confounding. Their recommendation aligns with many who seek a scientific yet compassionate guide to navigating loss. This perspective invites you to explore how the brain encodes love and loss, offering clarity during your own journey through grief.

Recommended by Oprah Daily

For those who want to understand what’s happening to them and why grief is so confounding, this is a fascinating and comforting read. (from Amazon)

2022·256 pages·Psychology, Human Brain, Loss, Neuroscience, Emotional Processing

The breakthrough moment came when Mary-Frances O'Connor, a neuroscientist and psychologist, synthesized decades of grief research into a narrative that reveals how our brains process love and loss. You’ll discover why grief triggers a storm of emotions like guilt and anger, and why it can feel endless, as the brain struggles to accept absence and rebuild meaning. Chapters unpack distinctions between normal and prolonged grief, enriched by O'Connor’s neuroimaging studies and real-life stories that clarify how our neurons encode attachment and loss. This book suits anyone grappling with grief or seeking scientific insight into this deeply human experience.

NPR SciFri Book Club Pick
Next Big Idea Club's Top 21 Psychology Books of 2022
Behavioral Scientist Notable Books of 2022
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Best for mental health brain programs
Daniel G. Amen, MD, is a clinical neuroscientist and psychiatrist renowned for his work with brain imaging and mental health. Heading the Amen Clinics and recognized by The Washington Post as America's most popular psychiatrist, Dr. Amen draws on decades of experience and over 100,000 brain scans to craft this book. His unique perspective offers readers brain-based methods to address anxiety, depression, memory issues, and more, making this a valuable guide for those interested in the intersection of neuroscience and everyday mental wellness.
2015·480 pages·Human Brain, Neuro-psychiatry, Neuropsychiatry, Mental Health, Anxiety Management

What happens when clinical neuroscience meets practical mental health? Daniel G. Amen, MD, leverages over 100,000 brain scans to connect specific brain functions with conditions like anxiety, depression, and memory problems. You’ll find targeted strategies here—like breathing techniques to calm anxiety, dietary advice to manage anger, and exercises to improve focus—that hinge on understanding your brain’s unique wiring. This book suits anyone grappling with emotional or cognitive challenges curious about how brain health directly influences behavior and mood.

New York Times Bestseller
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Best for neuroscience and spirituality
Anatomy of the Soul stands out in the human brain category for its unique integration of neuroscience with Christian spirituality, offering insights into how spiritual practices can physically reshape your brain. This approach has resonated with many readers who want to improve their relationships and personal growth by understanding the brain’s role in transformation. Curt Thompson, M.D., combines accessible explanations of brain science with practical methods involving scripture and interpersonal connection, making complex concepts approachable. This book addresses the often-overlooked spiritual dimension of mental health, providing a fresh perspective for those seeking change that aligns with both faith and science.
2010·282 pages·Human Brain, Neuroscience, Spirituality, Personal Transformation, Attachment Theory

Drawing from his medical background in psychiatry and deep interest in spirituality, Curt Thompson explores how neuroscience intersects with Christian practices to foster personal transformation. You’ll discover how the brain’s wiring can change through spiritual disciplines and meaningful relationships, shifting patterns that shape your identity and interactions. For example, Thompson explains how engaging with Scripture and others can literally rewire brain pathways, promoting healing and growth. This book suits anyone curious about the blend of science and faith, especially those seeking to deepen their relationships and personal development through an anchored understanding of the mind.

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Conclusion

These 10 books weave together themes of brain adaptability, emotional insight, and practical brain health strategies, all validated by experts and millions of readers. If you're drawn to proven methods, The Brain That Changes Itself and Head Strong offer deep dives into neuroplasticity and cognitive enhancement. For those wanting validated approaches to mental wellness, Change Your Brain, Change Your Life and Brain Lock provide actionable programs.

To balance scientific rigor with personal meaning, Anatomy of the Soul bridges neuroscience and spirituality, while The Grieving Brain illuminates how loss reshapes our minds. Alternatively, you can create a personalized Human Brain book to blend these proven insights uniquely suited to you.

These widely-adopted approaches have helped countless readers understand and care for their brains in meaningful ways—your journey to deeper brain knowledge and health starts here.

Frequently Asked Questions

I'm overwhelmed by choice – which book should I start with?

Start with How Emotions Are Made for a foundational understanding of brain and emotion, recommended by experts like Daniel Gilbert. It offers a broad yet insightful look that sets the stage for deeper exploration.

Are these books too advanced for someone new to the human brain?

Not at all. Many books, such as The Brain That Changes Itself, use engaging stories and clear language, making complex neuroscience accessible for beginners.

Do I really need to read all of these, or can I just pick one?

You can pick based on your interest. For brain health, try Head Strong; for emotional insight, choose How Emotions Are Made. Each offers focused, expert-backed content.

Which books focus more on theory vs. practical application?

How Emotions Are Made leans toward theory, exploring neuroscience and culture, while Change Your Brain, Change Your Life offers practical strategies for mental health.

Are any of these books outdated given how fast brain science changes?

These selections include recent and enduring works that remain relevant, blending foundational science with updated research and applications.

Can personalized books complement these expert recommendations?

Yes! While these books provide expert insights, a personalized Human Brain book tailors content to your goals and background, enhancing how you apply proven methods. See create your custom guide for more.

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