20 Human Brain Books That Change How You Think
Recommended by Bill Gates, David Perlmutter, and Lewis Howes, these Human Brain books unlock new understanding and practical insights.

What if your brain held secrets that could transform how you think, feel, and learn? The human brain remains one of the most astonishing frontiers of science, with discoveries reshaping our understanding daily. From emotional construction to brain plasticity, the questions about how our minds work fuel curiosity and drive innovation.
Leading thinkers like Bill Gates, David Perlmutter, and Lewis Howes have turned to specific books that unpack these mysteries. Gates highlights how novel theories in "A Thousand Brains" illuminate intelligence, while Perlmutter champions "You, Happier" for its neuroscience-backed happiness strategies. Their expert insights, drawn from years of experience and research, provide a trustworthy compass in the complex landscape of brain science.
These 20 books offer frameworks that not only delve into theory but also provide actionable approaches to brain health, cognition, and emotional resilience. While these expert-curated selections guide you through proven concepts, you might consider creating a personalized Human Brain book that adapts this knowledge to your unique background, goals, and interests for a truly tailored learning journey.
Recommended by David Perlmutter
Board-certified neurologist, bestselling author
“Dr. Amen eloquently reveals the simple and yet profound notion that happiness can be cultivated. We’ve long had the tools to achieve important goals like losing weight and gaining strength, but the science underlying how we can bring about brain changes to create and enhance happiness has remained obscure until now. You, Happier is your guide to make happiness manifest in your life. And why not?”
by MD Amen Daniel G.··You?
by MD Amen Daniel G.··You?
After analyzing more than 200,000 brain scans from 155 countries, Dr. Daniel Amen developed a neuroscience-based framework that identifies five distinct brain types influencing happiness. In this book, he guides you through seven brain-centered habits and daily questions tailored to your brain type, helping you improve mood and brain health. You’ll learn to recognize your brain's unique wiring and adopt strategies that foster consistent happiness, moving beyond generic advice. For anyone curious about the neurological roots of well-being and seeking personalized tools to boost joy, this book offers clear insights grounded in extensive research.
Recommended by Daniel Schacter
Harvard University cognitive psychologist
“Stephen Grossberg is one of the most original and influential theorists in contemporary cognitive science and computational neuroscience. In Conscious MIND Resonant BRAIN, he takes the reader on an eye-opening tour in which he addresses fundamental problems of mind and brain from his unique theoretical perspective. This is an important book that should be of interest to anyone who wonders how a brain can give rise to a mind.”
by Stephen Grossberg··You?
by Stephen Grossberg··You?
Drawing from five decades of pioneering research in neural networks and cognitive science, Stephen Grossberg unpacks the intricate relationship between brain structures and conscious experience. You’ll explore detailed models explaining how multiple brain regions collaborate to generate perception, memory, decision-making, and even moral values. For example, chapters delve into neural mechanisms behind disorders like Alzheimer's and autism, while others bridge insights into artificial intelligence design. If you seek a deep understanding of how physical brain processes translate into mental phenomena, this book offers a rigorous yet accessible guide, though it demands patience and a willingness to engage with complex scientific ideas.
by TailoredRead AI·
by TailoredRead AI·
This tailored book explores the full spectrum of human brain functions and health, designed to focus on your unique interests and background. It covers fundamental neuroscience concepts, brain anatomy, cognitive processes, neuroplasticity, and emotional regulation, weaving these themes into a cohesive guide that matches your specific goals. By synthesizing collective expert knowledge into a personalized narrative, it reveals how different brain areas contribute to cognition, behavior, and wellness, helping you grasp complex topics with clarity. This personalized journey enables a deeper understanding of brain mechanisms and practical insights aligned directly to what you want to learn, making the science of the brain accessible and engaging.
Recommended by Emmanuel Acho
Former NFL player, sports analyst
“After my years playing professional football in the NFL, I took a deep dive into studying the most important organ in my body: the brain. Thankfully, I came across Dr. Willeumier, the foremost expert on research, knowledge, and practical ways to regenerate and revitalize the most valuable asset we each possess. Her passion for and dedication to helping and healing athletes’ brain function is unparalleled, and I am thrilled that you each get to receive some of the wisdom that she has blessed me with over the years.”
by Kristen Willeumier··You?
by Kristen Willeumier··You?
Dr. Kristen Willeumier, a neuroscientist with extensive research experience at UCLA and Cedars-Sinai, wrote this book to bridge the gap between cutting-edge brain science and everyday health practices. You learn how lifestyle tweaks—like targeted nutrition, cognitive exercises, and physical activity—can enhance memory, reduce stress, and even counteract brain injuries or neurodegenerative risks. Chapters include practical insights into supplements and brain games, backed by her clinical work with NFL players and patients. This book suits anyone wanting to proactively maintain or improve cognitive function, from athletes to those concerned about aging or recovery from brain trauma.
Recommended by Bill Gates
Co-Founder & Former CEO of Microsoft
“[F]illed with fascinating insights into the architecture of the brain and tantalizing clues about the future of intelligent machines.”
by Jeff Hawkins, Richard Dawkins··You?
by Jeff Hawkins, Richard Dawkins··You?
Drawing from decades of neuroscience and computer engineering expertise, Jeff Hawkins coalesces his groundbreaking research into a theory revealing the brain’s use of numerous maplike models to interpret the world. You’ll uncover why intelligence is more distributed and dynamic than previously thought, exploring concepts such as the brain’s layered model-building and the emergence of self-awareness. The book demystifies complex neuroanatomy and high-level cognition through accessible explanations and examples, like the brain’s grid cells and their role in perception. If you’re fascinated by cognitive science or AI’s future, this book offers a fascinating window into how intelligence is architected at a cellular level.
Recommended by Kirk Borne
Principal Data Scientist at Booz Allen
“As AI moves toward AGI with Neural Networks, deeper understanding of Emotion Science is critical! See "How Emotions Are Made — The Secret Life of the Brain" by Lisa Feldman Barrett. Get the book and watch her amazing TED Talk.” (from X)
by Lisa Barrett··You?
Lisa Feldman Barrett’s decades of pioneering research reshaped how we understand emotions, challenging the idea that they are hardwired responses. In this book, you’ll discover how emotions emerge from complex interactions among your brain, body, and cultural context, rather than being fixed reactions. She explains concepts like the brain’s predictive coding and how cultural differences shape emotional experiences, offering a fresh lens on psychology and neuroscience. If you want to grasp why emotions feel so personal yet are constructed, this book guides you through that intricate process with clarity and scientific rigor.
by TailoredRead AI·
by TailoredRead AI·
This tailored book explores targeted methods to enhance memory, focus, and mental clarity through a personalized lens. It covers cognitive techniques and neuroscience insights that match your interests and background, providing a clear pathway to sharpen your brain’s performance. You’ll engage with content that examines how attention, memory retention, and mental agility can be improved based on your specific goals and current abilities. By focusing on your unique cognitive profile, this tailored guide reveals practical ways to boost brain power effectively and sustainably. It offers an exciting, focused journey through the complex landscape of cognitive enhancement tailored just for you.
Recommended by Jennifer Gunter
OB/GYN and NYT contributor
“And the book The XX Brain by Dr. Mosconi great read and she is doing some amazing research.” (from X)
by Lisa Mosconi PhD, Maria Shriver··You?
by Lisa Mosconi PhD, Maria Shriver··You?
The XX Brain emerges from Dr. Lisa Mosconi's extensive neuroscience research, particularly focused on women's unique brain health challenges. You learn why estrogen and the XX chromosome shape cognitive resilience and risk, with detailed chapters on diet, stress reduction, sleep, and hormonal balance tailored specifically for women. Mosconi confronts common misconceptions about brain fog, menopause, and Alzheimer's risks, offering evidence-based insights that go beyond generic advice. If you want to understand how your brain's biology interacts with lifestyle and aging—and what you can realistically do about it—this book offers a clear, focused guide rooted in scientific study and clinical experience.
Recommended by Maria Shriver
American journalist and activist
“If we want to care for our minds, then we have to be mindful about what we eat. Dr. Perlmutter understands the connection between diet and brain health, and this revised edition of Grain Brain teaches us that simple lifestyle changes can make a world of difference.”
by David Perlmutter MD··You?
by David Perlmutter MD··You?
David Perlmutter, MD, a neurologist and nutrition expert awarded the Linus Pauling Award, challenges conventional wisdom by linking carbs, especially gluten and sugar, to brain inflammation and neurological disorders. You’ll explore how everyday foods can influence conditions like dementia, anxiety, and chronic headaches, and learn a 4-week plan emphasizing healthy fats to support brain cell growth and cognitive vitality. Chapters detail how statins may affect memory and provide recipes and goals to help you implement dietary changes. This book suits those interested in understanding brain health beyond genetics and who want a diet-based approach to mental wellness.
Recommended by David Perlmutter
Board-certified neurologist and author
“Dave Asprey has masterfully utilized leading edge neuroscience as well as his extensive personal experience to create a user-friendly guide that will clearly fulfill its promise to protect, restore, and enhance brain function. Head Strong is a tour de force.”
by Dave Asprey··You?
What started as Dave Asprey's quest to enhance human performance led to this focused guide on boosting brain energy and clarity in just two weeks. Drawing from years of collaboration with top scientists and doctors, Asprey breaks down how to fuel your brain effectively, eliminate mental slowdowns caused by diet and environment, and stimulate neuron growth to sharpen cognitive speed. You’ll find detailed lifestyle adjustments—from nutrition to lighting—that aim to optimize your mental stamina and resilience. This book suits anyone wanting a practical yet science-backed approach to enhance cognitive function without getting lost in jargon or overly technical explanations.
Recommended by Vinod Khosla
Partner at Khosla Ventures
by Jonah Lehrer··You?
by Jonah Lehrer··You?
The breakthrough moment came when Jonah Lehrer, a Rhodes Scholar and editor at large for Seed magazine, bridged neuroscience with everyday decision-making. Drawing from his work with Nobel laureate Eric Kandel and contributions to major publications, Lehrer dives into how your brain blends emotion and reason uniquely in each choice. You'll learn when to trust intuition—like buying a house—and when to engage deliberate thought—such as stock picking. With vivid examples including pilots, investors, and poker players, this book offers concrete insights into sharpening your decision process. If you're curious about the science behind your choices and want a nuanced guide to thinking smarter, this is for you.
by Hal Blumenfeld··You?
by Hal Blumenfeld··You?
Hal Blumenfeld's extensive experience as a neurologist and neuroscientist shapes this immersive guide to neuroanatomy, grounding complex concepts in real-world clinical cases. You’ll explore over 100 detailed patient scenarios alongside radiologic images, which not only illustrate structural brain details but also highlight their functional significance. The third edition introduces updated advances and fresh cases, reinforcing your understanding of how different brain systems interconnect and impact clinical outcomes. This book suits medical students, clinicians, and anyone aiming to bridge theory with practical neuroanatomical application, though its depth may challenge casual learners.
Recommended by Amanda Ripley
New York Times best-selling author
“A spellbinding investigation into the mysteries of the human brain, led by a scientist whose tenacity is as remarkable as her story.”
by Barbara K. Lipska, Elaine McArdle··You?
by Barbara K. Lipska, Elaine McArdle··You?
What happens when a neuroscientist becomes a patient? Barbara K. Lipska, director of the Human Brain Collection Core at the National Institute of Mental Health, offers a rare window into the brain’s fragility and resilience through her own battle with metastatic melanoma in the frontal lobe. You’ll learn how brain cancer can mimic psychiatric disorders like schizophrenia, a field Lipska has studied extensively, and how immunotherapy influences cognitive and behavioral functions. Chapters detail her gradual loss of self-awareness and eventual recovery, weaving scientific insight with personal narrative. This book suits anyone intrigued by brain science, mental illness, or the human experience of illness and recovery.
Recommended by Preston Pysh
Aerospace engineer and investor, podcast host
“@RayDalio So true Ray! I recently read an amazing book on the subconscious that you would really enjoy. It's called, Consciousness and the Brain: Deciphering How the Brain Codes Our Thoughts.” (from X)
by Stanislas Dehaene··You?
by Stanislas Dehaene··You?
What started as a quest to pinpoint consciousness’s biological roots became a rigorous exploration led by Stanislas Dehaene, a top cognitive psychologist and neuroimaging expert. In this book, you’ll discover how techniques like functional magnetic resonance imaging reveal the brain’s long-distance communication networks, shedding light on how thoughts are coded neurologically. Dehaene’s global neuronal workspace theory is a highlight, explaining consciousness as a broadcast system within the brain, with detailed chapters on pyramidal neurons and their specialized roles. If you're keen to understand the intersection of neuroscience and consciousness from a scientific perspective, this book offers sharp insights, though it’s best suited for readers comfortable with technical detail rather than casual overviews.
Recommended by Elizabeth Kolbert
Pulitzer Prize–winning author
“At moments of extreme exasperation, parents may think that there’s something wrong with their teenagers’ brains. Which, according to recent books on adolescence, there is…. Jensen offers a parenting guide laced with the latest MRI studies…. Packed with charts and statistics.”
by Frances E Jensen, Amy Ellis Nutt··You?
by Frances E Jensen, Amy Ellis Nutt··You?
Frances E. Jensen’s decades of neuroscience research, combined with her experience as a mother, shaped this revealing exploration of adolescent brain development. You learn how teens' brains differ fundamentally from adults', from heightened memory-building abilities to vulnerabilities like addiction and stress response, with chapters unpacking topics such as multitasking effects and gender-related maturity differences. This book is especially useful if you’re a parent, educator, or anyone working closely with teenagers, offering insights that challenge common misconceptions and better equip you to understand teen behavior. For example, Jensen explains why occasional marijuana use can have lasting impacts on the young brain—details grounded in recent MRI studies that make complex science relatable and actionable.
Recommended by Oprah Daily
“For those who want to understand what’s happening to them and why grief is so confounding, this is a fascinating and comforting read.”
by Mary-Frances O'Connor··You?
by Mary-Frances O'Connor··You?
When Mary-Frances O’Connor, a neuroscientist and psychologist, first uncovered how grief reshapes neural pathways, she set out to illuminate the complex interplay between love, loss, and brain function. You’ll explore the neuroscience behind why it’s so difficult to accept a loved one’s permanent absence and the emotional turbulence that follows, from guilt to yearning. The book explains distinctions like typical versus prolonged grief, backed by O’Connor’s neuroimaging research and real-life examples that clarify how the brain processes attachment and recovery. If you’re trying to understand your own grief or support someone through loss, this book offers clear insights into how the human brain learns from such profound experiences.
Recommended by David McRaney
Best-selling author of You Are Not So Smart
“If you’ve ever wanted to sit down with a neuroscientist, have a few drinks, ask a zillion questions, and laugh until you snorted, read this book.”
by Dean Burnett··You?
by Dean Burnett··You?
Dean Burnett's background as a neuroscientist and comedic writer shines through in this engaging exploration of the brain's quirks and flaws. You get a clear-eyed look at how your mind often misfires—forgetting names, replaying fears, or clinging to outdated instincts—while still managing to keep you functioning. The book balances humor with neuroscience, offering insights into why your brain sometimes seems to sabotage you, like the chapter dissecting insomnia's paradoxical nature. If you want to understand your brain’s odd behaviors without jargon overload, this is a fit. However, if you're seeking deeply technical neuroscience, this book leans more toward accessible storytelling than dense science.
Recommended by Rand Fishkin
Founder and former CEO of Moz
by David Eagleman··You?
by David Eagleman··You?
What if everything you knew about your conscious mind was only scratching the surface? David Eagleman, a neuroscientist at Stanford University, delves beneath awareness to reveal the hidden workings of the subconscious brain. You’ll explore why your body reacts before your mind catches up, the quirks of perception like synesthesia, and how our brains wrestle with identity, decision-making, and even secrets. Chapters on topics from criminal law to artificial intelligence illustrate the brain’s surprising contradictions, offering insights that benefit anyone curious about mental processes, from psychology enthusiasts to professionals in neuroscience and law.
by Todd D. Zakrajsek··You?
by Todd D. Zakrajsek··You?
Unlike most human brain books that focus narrowly on theory, Todd D. Zakrajsek, drawing on his extensive experience in faculty development at the University of North Carolina, offers a pragmatic approach to learning that aligns directly with how your brain functions. You’ll unpack chapters on sleep cycles, exercise’s role in memory, and mindset shifts, but also delve into challenges posed by online learning environments and group dynamics. Specific strategies for designing personalized learning plans and avoiding common cognitive pitfalls make this a resource tailored for anyone aiming to improve academic performance and retention, particularly those new to higher education settings.
Recommended by Preston Pysh
Aerospace engineer & investor, podcast host
“@RolandDPT @Breedlove22 Yes, I’ve read it. Very fascinating book.” (from X)
by Norman Doidge··You?
Drawing from his extensive background as a psychiatrist and psychoanalyst, Norman Doidge challenges the old belief that the brain is fixed and unchangeable. Through detailed stories, you learn how neuroplasticity allows the brain to rewire itself in surprising ways, from stroke recovery to overcoming learning disorders. Chapter 3, for example, explores how blind individuals can develop sight-like abilities, illustrating the brain's adaptability. This book suits anyone curious about brain science or seeking hope in neurological rehabilitation, offering a grounded look at what the brain can achieve without overpromising miracles.
Recommended by Arianna Huffington
Co-founder of The Huffington Post
“In her remarkable new book “The Neuroscience of You,” Chantel Prat writes, “When we embrace the fact that no two brains are alike, we're better able to understand ourselves and how we experience the world around us.”” (from X)
by Chantel Prat·You?
What started as a challenge to traditional neuroscience assumptions led Chantel Prat, a University of Washington professor, to explore how no two brains function alike. This book guides you through understanding your unique brain traits, from attention patterns to social navigation, with quizzes and real-life examples like the “Focus” and “Connect” chapters. You'll gain specific insights into how your brain’s wiring affects learning, decision-making, and relationships. If you want to see beyond averages and appreciate the quirks that define your mental processes, this book offers a straightforward, science-backed perspective.
Recommended by Imani Perry
Hughes Rogers Professor, Princeton University
“Such a fascinating and elegant book” (from X)
by Moheb Costandi··You?
by Moheb Costandi··You?
What if everything you knew about brain change was wrong? Moheb Costandi, who pens the Neurophilosophy blog for The Guardian, unpacks decades of neuroscience research to show how our brains and nervous systems remain dynamic throughout life. You’ll gain insights into key mechanisms like synaptic pruning, adult neurogenesis, and how complex learning—whether mastering a language or navigating London’s streets—physically reshapes brain structure. Costandi also explores brain recovery after injury and how maladaptive neuroplasticity underlies addiction and pain, making this a clear-eyed exploration for anyone curious about the biological roots of human adaptability. This book suits those looking to understand the science behind brain change rather than quick fixes or gimmicks.
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Conclusion
This collection highlights three clear themes: the brain's remarkable adaptability, the intricate ties between emotion and cognition, and the importance of personalized approaches to brain health. If you're seeking to understand your brain's unique wiring, start with "The Neuroscience of You" and "You, Happier" for insights grounded in individuality and happiness.
For those aiming to optimize mental performance swiftly, "Head Strong" and "Biohack Your Brain" offer practical strategies backed by scientific research. Meanwhile, if you're fascinated by foundational neuroscience or clinical applications, "Neuroanatomy through Clinical Cases" and "Conscious Mind, Resonant Brain" provide deep explorations.
Alternatively, you can create a personalized Human Brain book to connect general principles with your specific needs, accelerating your learning and enhancing application. These books can help you accelerate your learning journey and deepen your understanding of the most complex organ in the body.
Frequently Asked Questions
I'm overwhelmed by choice – which book should I start with?
Start with "You, Happier" for a personalized approach to brain-based happiness or "The Neuroscience of You" to understand your unique brain traits. These offer accessible insights and set a solid foundation for exploring brain science further.
Are these books too advanced for someone new to Human Brain?
Not at all. Several selections like "Idiot Brain" and "How Emotions Are Made" explain complex ideas in clear, engaging ways, making them perfect for beginners eager to learn without jargon overload.
What's the best order to read these books?
Begin with books that focus on personal brain understanding and health, such as "You, Happier" and "Biohack Your Brain," then progress to more theoretical works like "Conscious Mind, Resonant Brain" and "A Thousand Brains" as your curiosity deepens.
Should I start with the newest book or a classic?
A balanced approach works best. Newer books like "Biohack Your Brain" provide up-to-date practical advice, while classics such as "The Brain That Changes Itself" offer foundational insights into neuroplasticity valuable for all readers.
Do these books assume I already have experience in Human Brain?
Most are written to be approachable without prior expertise. Authors like Dean Burnett in "Idiot Brain" and Frances Jensen in "The Teenage Brain" explain concepts clearly, welcoming readers at various knowledge levels.
How can I get brain insights tailored to my unique interests and goals?
While these expert books provide broad frameworks, you can create a personalized Human Brain book that takes your background and goals into account, bridging expert knowledge with your personal application for focused learning.
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